Just got a chance to try MSE against a real virus that infected my Vista OS on my laptop.
First did a quick scan, and it found a couple of trojans pretty quick, and removed them.
I then started a full scan, as there was still crap on my computer (i.e. popups from a fake antivirus software saying I'm infected, I'm getting attacks from this port on that port, etc., and that last one even with the internet connection disabled by unplugging the modem), and it was barely a quarter done scanning six hours laters, so I canceled it, rebooted, and went into Ubuntu, which is where I'm at now. I'll give it another go tomorrow.
Funny...stupid virus on my computer was named "Vista Security Tool 2010" or some shit. The piece of crap kept getting in my way while I was doing the scan (even when in safe mode), was screwing with my browser, kept showing annoying popups saying that I was infected, and needed to run a scan, which I only tried once (before I realized it was part of the virus), and the thing claimed it found a bunch of infections, but it makes you register (which is not free). GOD, what kind of people write viruses, anyway?
Anyway, I tried to kill the process from the task manager, which sort of worked, but the damn thing kept getting started again somehow. The process name was "ave.exe". Another thing about this particular virus is it attached itself to Microsoft Defender, to where it completely owned it, and it wouldn't let you select a different antivirus or firewall through it. It insisted on selecting "Vista Security Tool 2010" and it advised me to turn it on. God, that crap is annoying...
Probably the most annoying thing about it all was I was trying to print something off from Vista which I can't do from Ubuntu, because my printer doesn't work from there, and had to go off somewhere with the papers in hand, and I ended up having to leave without my paper, because of the crap virus that took over my computer (or Vista, anyway).
Man, what part of "Safe Mode" is actually safe, anyway, if some viruses can still run under it?